KIR2DL1

Function

Receptor on natural killer (NK) cells for some HLA-C alleles such as w4 and w6. Inhibits the activity of NK cells thus preventing cell lysis.

Sequence Similarities

Belongs to the immunoglobulin superfamily.

Tissue Specificity

Expressed by NK cells.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

CD158a, CD158A, NKAT1, KIR2DL1, Killer cell immunoglobulin-like receptor 2DL1, CD158 antigen-like family member A, Natural killer-associated transcript 1, p58 natural killer cell receptor clones CL-42/47.11, p58.1 MHC class-I-specific NK receptor, NKAT-1, p58 NK receptor CL-42/47.11

Database links

swissprot:P43626 omim:604936 entrezGene:3802

Other research areas

• Immunology & Infectious Disease