KIR2DL3

Function

Receptor on natural killer (NK) cells for HLA-C alleles (HLA-Cw1, HLA-Cw3 and HLA-Cw7). Inhibits the activity of NK cells thus preventing cell lysis.

Sequence Similarities

Belongs to the immunoglobulin superfamily.

Cellular localization

• Cell membrane
• Single-pass type I membrane protein

Alternative names

CD158b2, CD158B2, KIRCL23, NKAT2, KIR2DL3, Killer cell immunoglobulin-like receptor 2DL3, CD158 antigen-like family member B2, KIR-023GB, Killer inhibitory receptor cl 2-3, NKAT2a, NKAT2b, Natural killer-associated transcript 2, p58 natural killer cell receptor clone CL-6, p58.2 MHC class-I-specific NK receptor, NKAT-2, p58 NK receptor CL-6

Database links

swissprot:P43628 entrezGene:3805 omim:604938 omim:604936 omim:604945 omim:604955 swissprot:P43626 swissprot:P43632 swissprot:Q99706 entrezGene:3802 entrezGene:3804 entrezGene:3809