KIR3DL1
Domain
Ig-like C2-type domain 2 mediates specificity through recognition of the Bw4 epitope.
Function
Receptor on natural killer (NK) cells for HLA Bw4 allele. Inhibits the activity of NK cells thus preventing cell lysis.
Sequence Similarities
Belongs to the immunoglobulin superfamily.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
Alternative names
CD158e, CD158E, NKAT3, NKB1, KIR3DL1, Killer cell immunoglobulin-like receptor 3DL1, CD158 antigen-like family member E, HLA-BW4-specific inhibitory NK cell receptor, Natural killer-associated transcript 3, p70 natural killer cell receptor clones CL-2/CL-11, NKAT-3, p70 NK receptor CL-2/CL-11