KLC1
Function
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport (PubMed:21385839). The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity (By similarity).
Post-translational modifications
Phosphorylation at Ser-460 by ERK inhibits interaction with CLSTN1 and localization to cytoplasmic vesicles.
Sequence Similarities
Belongs to the kinesin light chain family.
Tissue Specificity
Found in a variety of tissues. Mostly abundant in brain and spine.
Cellular localization
- Cell projection
- Growth cone
- Cytoplasmic vesicle
- Cytoplasm
- Cytoskeleton
Alternative names
KLC, KNS2, KLC1, Kinesin light chain 1, KLC 1