KLF9
Function
Transcription factor that binds to GC box promoter elements. Selectively activates mRNA synthesis from genes containing tandem repeats of GC boxes but represses genes with a single GC box. Acts as an epidermal circadian transcription factor regulating keratinocyte proliferation (PubMed:22711835).
Sequence Similarities
Belongs to the Sp1 C2H2-type zinc-finger protein family.
Tissue Specificity
Epidermis (at protein level).
Cellular localization
- Nucleus
Alternative names
BTEB, BTEB1, KLF9, Krueppel-like factor 9, Basic transcription element-binding protein 1, GC-box-binding protein 1, Transcription factor BTEB1, BTE-binding protein 1