Klrb1c

Function

Plays a stimulatory role on natural killer (NK) cells cytotoxicity. Activation by cross-linking of the receptor induces Ca(2+) mobilization and interferon-gamma production.

Tissue Specificity

Expressed in natural killer cells.

Cellular localization

• Membrane
• Single-pass type II membrane protein

Alternative names

CD161c, Ly55c, Nkrp1c, Klrb1c, Killer cell lectin-like receptor subfamily B member 1C, CD161 antigen-like family member C, Lymphocyte antigen 55c, NK1.1, NKR-P1.9, NKR-P1C, Natural killer cell surface protein P1-40, Ly-55c, NKR-P1 40

Database links

swissprot:P27814 entrezGene:17059

Other research areas

• Immuno-oncology