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Krt19

Developmental stage

Expressed throughout embryonic development with highest levels at 8.5 dpc. Expression decreases by 11.5 dpc and increases again by 17.5 dpc.

Domain

This keratin differs from all other IF proteins in lacking the C-terminal tail domain.

Function

Involved in the organization of myofibers. Together with KRT8, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle (By similarity).

Sequence Similarities

Belongs to the intermediate filament family.

Alternative names

Krt1-19, Krt19, Cytokeratin-19, Keratin-19, CK-19, K19

swissprot:P19001 entrezGene:16669