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KRT40

Developmental stage

During differentiation of the hair, it is one of the last keratins expressed.

Function

May play a role in late hair differentiation.

Sequence Similarities

Belongs to the intermediate filament family.

Tissue Specificity

Expressed in skin and scalp. Also very weakly expressed in tongue, breast, colon and small intestine. In the hair follicle, it is specifically present in the upper hair cuticle. Not present in the upper cortex (at protein level).

Alternative names

KA36, KRT40, Cytokeratin-40, Keratin-40, Type I hair keratin Ka36, CK-40, K40

swissprot:Q6A162 entrezGene:125115