Krt7
Function
Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
Post-translational modifications
Arg-15 is dimethylated, probably to asymmetric dimethylarginine.
Sequence Similarities
Belongs to the intermediate filament family.
Tissue Specificity
Expressed in most simple epithelia tested including liver, lactating mammary gland, lung, kidney, stomach, duodenum, colon, oviduct, uterus, pancreas, epididymis, prostate, preputial gland and mesothelium, and in most stratified epithelia tested including dorsal skin, paw/toe, tail, tongue, cervix, forestomach, and bladder. Also expressed in Henle layer of the inner root sheath of whisker follicle.
Alternative names
Krt2-7, Krt7, Cytokeratin-7, Keratin-7, Type-II keratin Kb7, CK-7, K7