KRTAP11-1
Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Sequence Similarities
Belongs to the PMG family.
Tissue Specificity
Expressed in the upper matrix and in the entire hair cortex.
Alternative names
KAP11.1, KRTAP11.1, KRTAP11-1, Keratin-associated protein 11-1, High sulfur keratin-associated protein 11.1