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LALBA

Function

Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N-acetylglucosamine of the oligosaccharide chains in glycoproteins.

Sequence Similarities

Belongs to the glycosyl hydrolase 22 family.

Tissue Specificity

Mammary gland specific. Secreted in milk.

Cellular localization

Alternative names

ALACTA, LALBA, Alpha-lactalbumin, Lactose synthase B protein

swissprot:P00711 entrezGene:281894