lcp1
Developmental stage
Expressed in macrophage precursors as they migrate from the midline to the yolksac during somatogenesis. Prior to blood circulation, continues to be expressed in maturing macrophage precursors in the yolksac and in those that have migrated to the mesenchyme of the head. At 28 hours post-fertilization (hpf), also expressed in the caudal part of the axial vein and the surrounding mesenchyme.
Function
Actin-binding protein. Plays a role in the activation of T-cells (By similarity).
Tissue Specificity
Expressed by macrophages (at protein level).
Cellular localization
- Cytoplasm
- Cytoskeleton
- Cell junction
- Cell projection
- Cell projection
- Ruffle membrane
- Peripheral membrane protein
- Cytoplasmic side
Alternative names
pls2, lcp1, Plastin-2, L-plastin, Lymphocyte cytosolic plastin 1