Skip to main content

L-lactate dehydrogenase B

Involvement in disease

Lactate dehydrogenase B deficiency

LDHBD

A condition with no deleterious effects on health. LDHBD is of interest to laboratory medicine mainly because it can cause misdiagnosis in those disorders in which elevation of serum LDH is expected.

None

The disease is caused by variants affecting the gene represented in this entry.

Pathway

Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.

Sequence similarities

Belongs to the LDH/MDH superfamily. LDH family.

Cellular localization

  • Cytoplasm
  • Mitochondrion inner membrane
  • Peripheral membrane protein

Alternative names

  • L-lactate dehydrogenase B chain
  • LDH-B
  • LDH heart subunit
  • Renal carcinoma antigen NY-REN-46
  • LDH-H
  • LDHB

Target type

Proteins

Primary research area

Immuno-oncology

Other research areas

  • Immunology & Infectious Disease
  • Oncology

Molecular weight

36638Da