LGALS7

Function

Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Tissue Specificity

Mainly expressed in stratified squamous epithelium.

Cellular localization

• Cytoplasm
• Nucleus
• Secreted
• May be secreted by a non-classical secretory pathway.

Alternative names

PIG1, LGALS7B, LGALS7, Galectin-7, Gal-7, HKL-14, PI7, p53-induced gene 1 protein

Database links

swissprot:P47929 omim:600615 entrezGene:3963 entrezGene:653499