LHB

Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids.

Hypogonadotropic hypogonadism 23 with or without anosmia

HH23

A form of hypogonadotropic hypogonadism, a group of disorders characterized by absent or incomplete sexual maturation by the age of 18 years, in conjunction with low levels of circulating gonadotropins and testosterone and no other abnormalities of the hypothalamic-pituitary axis. HH23 male patients have normal sexual differentiation, reduced or absent Leydig cells, reduced or absent spermatogenesis, and absence of spontaneous puberty. Female patients exhibit normal pubertal development and menarche, followed by oligomenorrhea and anovulatory secondary amenorrhea.

None

The disease is caused by variants affecting the gene represented in this entry.

Belongs to the glycoprotein hormones subunit beta family.

Pituitary gland.

• Secreted

Lutropin subunit beta, Lutropin beta chain, Luteinizing hormone subunit beta, LH-B, LSH-B, LSH-beta, LHB

• entrezGene:3972
• omim:152780
• swissprot:P01229

Proteins

Developmental Biology

15345Da