ligA
Function
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
Sequence Similarities
Belongs to the NAD-dependent DNA ligase family. LigA subfamily.
Alternative names
CPS_3466, ligA, DNA ligase, Polydeoxyribonucleotide synthase [NAD(+)]