LILRB5
Domain
Contains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
Function
May act as receptor for class I MHC antigens.
Tissue Specificity
Detected in a natural killer (NK) cells.
Cellular localization
- Membrane
- Single-pass type I membrane protein
Alternative names
CD85c, LIR8, LILRB5, Leukocyte immunoglobulin-like receptor subfamily B member 5, CD85 antigen-like family member C, Leukocyte immunoglobulin-like receptor 8, LIR-8