LIN9
Function
Acts as a tumor suppressor. Inhibits DNA synthesis. Its ability to inhibit oncogenic transformation is mediated through its association with RB1. Plays a role in the expression of genes required for the G1/S transition.
Sequence Similarities
Belongs to the lin-9 family.
Tissue Specificity
Expressed in thymus and testis.
Cellular localization
- Nucleus
- Nucleoplasm
- Found in perinucleolar structures. Associated with chromatin.
Alternative names
BARA, TGS, LIN9, Protein lin-9 homolog, HuLin-9, hLin-9, Beta subunit-associated regulator of apoptosis, TUDOR gene similar protein, Type I interferon receptor beta chain-associated protein, pRB-associated protein