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Loricrin

Developmental stage

Expressed in the spinous and granular layers of the tongue at P20.

Function

Major keratinocyte cell envelope protein.

Post-translational modifications

Substrate of transglutaminases. Some glutamines and lysines are cross-linked to other loricrin molecules and to SPRRs proteins.

Contains inter- or intramolecular disulfide-bonds.

Tissue Specificity

Expressed in the epidermis of the ear (at protein level).

Alternative names

Lor, Loricrin

swissprot:P18165