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Function

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. May play a role in the development of ovarian cancer. Seems to be coupled to the G(i)/G(o) and G(q) families of heteromeric G proteins.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Tissue specificity

Most abundantly expressed in prostate, testes, pancreas, and heart, with moderate levels in lung and ovary. No detectable expression in brain, placenta, liver, skeletal muscle, kidney, spleen, thymus, small intestine, colon, or peripheral blood leukocytes.

Cellular localization

  • Cell membrane
  • Multi-pass membrane protein

Alternative names

EDG7, LPA3, LPAR3, Lysophosphatidic acid receptor 3, LPA receptor 3, LPA-3, Lysophosphatidic acid receptor Edg-7

Target type

Proteins

Primary research area

Immunology & Infectious Disease

Molecular weight

40128Da

We found 4 products in 2 categories

Primary Antibodies

Target

Application

Reactive species

Cell Lines & Lysates

Target

Cell type

Species or organism