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lplA

Function

Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes.

Pathway

Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.

Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.

Sequence Similarities

Belongs to the LplA family.

Cellular localization

Alternative names

BWG_4078, lplA, Lipoate-protein ligase A, Lipoate--protein ligase

swissprot:C4ZT68