LRFN2
Domain
The PDZ-binding motif is required for cell surface expression, neurite outgrowth promotion (By similarity). This motif is also involved in DLG1-, DLG3- and DLG4-binding.
Function
Promotes neurite outgrowth in hippocampal neurons. Enhances the cell surface expression of 2 NMDA receptor subunits GRIN1 and GRIN2A. May play a role in redistributing DLG4 to the cell periphery (By similarity).
Post-translational modifications
Glycosylated.
Sequence Similarities
Belongs to the LRFN family.
Cellular localization
- Membrane
- Single-pass type I membrane protein
- Synapse
- Postsynaptic cell membrane
Alternative names
KIAA1246, SALM1, LRFN2, Leucine-rich repeat and fibronectin type-III domain-containing protein 2, Synaptic adhesion-like molecule 1