LRIG3
Function
May play a role in craniofacial and inner ear morphogenesis during embryonic development. May act within the otic vesicle epithelium to control formation of the lateral semicircular canal in the inner ear, possibly by restricting the expression of NTN1 (By similarity).
Tissue Specificity
Widely expressed.
Cellular localization
- Cell membrane
- Single-pass type I membrane protein
- Cytoplasmic vesicle membrane
- Single-pass type I membrane protein
- Detected in cytoplasmic vesicles when coexpressed with ERBB4.
Alternative names
LIG3, UNQ287/PRO326/PRO335, LRIG3, Leucine-rich repeats and immunoglobulin-like domains protein 3, LIG-3