LRRC4C
Domain
The LRR region is both necessary and sufficient for the interaction with NTNG1.
Function
May promote neurite outgrowth of developing thalamic neurons.
Tissue Specificity
Highly expressed in the cerebral cortex, including frontal, parietal and occipital lobes. Putamen, amygdala, hippocampus and medulla oblongata show moderate expression. Caudate nucleus and thalamus express small amounts, whereas other brain regions show very weak or no expression.
Cellular localization
- Postsynaptic cell membrane
- Single-pass type I membrane protein
Alternative names
KIAA1580, NGL1, UNQ292/PRO331, LRRC4C, Leucine-rich repeat-containing protein 4C, Netrin-G1 ligand, NGL-1