LSM10
Function
Appears to function in the U7 snRNP complex that is involved in histone 3'-end processing. Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cell cycle progression from G1 to S phases. Binds specifically to U7 snRNA. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner.
Post-translational modifications
Not methylated. Methylation is not necessary for interaction with SMN.
Sequence Similarities
Belongs to the snRNP Sm proteins family.
Cellular localization
- Nucleus
Alternative names
U7 snRNA-associated Sm-like protein LSm10, LSM10