LSM3

Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320).

Belongs to the snRNP Sm proteins family.

• Nucleus

MDS017, LSM3, U6 snRNA-associated Sm-like protein LSm3

• entrezGene:27258
• omim:607283
• swissprot:P62310

Proteins

Immunology & Infectious Disease

11845Da