LST1

Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.

Belongs to the LST1 family.

Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain.

• Membrane
• Single-pass membrane protein
• Golgi apparatus membrane
• Single-pass membrane protein
• Endomembrane system
• Single-pass membrane protein
• Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.

B144, LST1, Leukocyte-specific transcript 1 protein, Protein B144

• entrezGene:7940
• omim:109170
• swissprot:O00453

Proteins

Immunology & Infectious Disease

10792Da