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LXN/TCI

Function

Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.

Sequence similarities

Belongs to the protease inhibitor I47 (latexin) family.

Tissue specificity

Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.

Cellular localization

  • Cytoplasm

Alternative names

  • Latexin
  • Endogenous carboxypeptidase inhibitor
  • Protein MUM
  • Tissue carboxypeptidase inhibitor
  • ECI
  • TCI
  • LXN

Target type

Proteins

Molecular weight

25750Da