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LXN

Function

Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.

Sequence Similarities

Belongs to the protease inhibitor I47 (latexin) family.

Tissue Specificity

Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain.

Cellular localization

Alternative names

Latexin, Endogenous carboxypeptidase inhibitor, Protein MUM, Tissue carboxypeptidase inhibitor, ECI, TCI, LXN

swissprot:Q9BS40 omim:609305 entrezGene:56925