LY75

Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.

N-glycosylated.

Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.

• Membrane
• Single-pass type I membrane protein

LY75, CD205, LY 75, Ly-75, gp200, CD 205, DEC205, CLEC13B, DEC 205, DEC-205, CLEC 13B, gp200 MR6, gp200-MR6, LY75_HUMAN, CD205 antigen, Lymphocyte antigen 75, Renal Cell Carcinoma (gp200), C-type lectin domain family 13 member B

• entrezGene:4065
• entrezGene:17076
• entrezGene:499800
• entrezGene:100526664
• omim:604524
• swissprot:O60449
• swissprot:Q60767

Proteins

215781Da