Ly86
Function
May cooperate with CD180 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) and cytokine production. Important for efficient CD180 cell surface expression.
Tissue Specificity
Highly expressed in spleen, liver, brain and thymus, and at lower levels in kidney.
Cellular localization
- Secreted
- Extracellular space
- Associated with CD180 at the cell surface.
Alternative names
Md1, Ly86, Lymphocyte antigen 86, Ly-86, Protein MD-1