MAN1A2
Function
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Pathway
Protein modification; protein glycosylation.
Sequence Similarities
Belongs to the glycosyl hydrolase 47 family.
Tissue Specificity
Highest levels of expression in placenta and testis.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
MAN1B, MAN1A2, Mannosidase alpha class 1A member 2