MAN2A1
Function
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Pathway
Protein modification; protein glycosylation.
Post-translational modifications
Glycosylated.
Sequence Similarities
Belongs to the glycosyl hydrolase 38 family.
Cellular localization
- Golgi apparatus membrane
- Single-pass type II membrane protein
Alternative names
MANA2, MAN2A1, Alpha-mannosidase 2, Golgi alpha-mannosidase II, Mannosidase alpha class 2A member 1, AMan II, Man II