Maob
Function
Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:4156831). Preferentially degrades benzylamine and phenylethylamine (By similarity).
Sequence Similarities
Belongs to the flavin monoamine oxidase family.
Cellular localization
- Mitochondrion outer membrane
- Single-pass type IV membrane protein
- Cytoplasmic side
Alternative names
Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B, Maob