Maob

Catalyzes the oxidative deamination of primary and some secondary amines such as neurotransmitters, and exogenous amines including the tertiary amine, neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), with concomitant reduction of oxygen to hydrogen peroxide and participates in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues (PubMed:11049757, PubMed:11134050, PubMed:20493079, PubMed:8316221, PubMed:8665924). Preferentially degrades benzylamine and phenylethylamine (PubMed:11049757, PubMed:11134050, PubMed:20493079, PubMed:8316221, PubMed:8665924).

Belongs to the flavin monoamine oxidase family.

• Mitochondrion outer membrane
• Single-pass type IV membrane protein
• Cytoplasmic side

Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B, MAOB

• entrezGene:4129
• omim:309860
• swissprot:P27338

Proteins

Immunology & Infectious Disease

58763Da