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MAP3K10

Function

Activates the JUN N-terminal pathway.

Post-translational modifications

Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation.

Sequence Similarities

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.

Tissue Specificity

Expressed in brain and skeletal muscle.

Alternative names

MLK2, MST, MAP3K10, Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST

swissprot:Q02779 omim:600137 entrezGene:4294