MAP4K5

Function

May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.

Sequence Similarities

Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.

Tissue Specificity

Ubiquitously expressed in all tissues examined, with high levels in the ovary, testis and prostate.

Cellular localization

• Cytoplasm

Alternative names

Mitogen-activated protein kinase kinase kinase kinase 5, Kinase homologous to SPS1/STE20, MAPK/ERK kinase kinase kinase 5, KHS, MEK kinase kinase 5, MEKKK 5, MAP4K5

Database links

swissprot:Q9Y4K4 entrezGene:11179 omim:604923 entrezGene:11183 swissprot:Q9NRM2