MBIP
Function
Inhibits the MAP3K12 activity to induce the activation of the JNK/SAPK pathway. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4.
Tissue Specificity
Ubiquitous. High expression seen in the heart and lung.
Cellular localization
- Nucleus
- Cytoplasm
- Shows a cytoplasmic localization when coexpressed with MAP3K12.
Alternative names
BM-015, MBIP, MAP3K12-binding inhibitory protein 1, MAPK upstream kinase-binding inhibitory protein, MUK-binding inhibitory protein