Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.
Belongs to the G-protein coupled receptor 1 family.
Expressed in the brain but not in the melanoma cells.
Melanocortin receptor 5, MC5-R, MC-2, MC5R
Proteins
Immunology & Infectious Disease
36601Da
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