MCHR1
Function
Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis.
Sequence Similarities
Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity
Highest level in brain, particularly in the frontal cortex and hypothalamus, lower levels in the liver and heart.
Cellular localization
- Cell membrane
- Multi-pass membrane protein
Alternative names
GPR24, SLC1, MCHR1, Melanin-concentrating hormone receptor 1, MCH receptor 1, MCH-R1, MCHR-1, G-protein coupled receptor 24, MCH-1R, SLC-1, Somatostatin receptor-like protein, MCH1R, MCHR