MDGA1
Function
Required for radial migration of cortical neurons in the superficial layer of the neocortex (By similarity). Plays a role in the formation or maintenance of inhibitory synapses. May function by inhibiting the activity of NLGN2.
Tissue Specificity
Has been found in brain, heart, skeletal muscle and kidney. Found to be overexpressed in tumor tissues.
Cellular localization
- Cell membrane
- Lipid-anchor
- GPI-anchor
- Associated with lipid rafts.
Alternative names
MAMDC3, MDGA1, MAM domain-containing glycosylphosphatidylinositol anchor protein 1, GPI and MAM protein, Glycosylphosphatidylinositol-MAM, MAM domain-containing protein 3, GPIM