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ME1

Function

Catalyzes the oxidative decarboxylation of (S)-malate in the presence of NADP(+) and divalent metal ions, and decarboxylation of oxaloacetate.

Sequence Similarities

Belongs to the malic enzymes family.

Tissue Specificity

Expressed in all tissues tested including liver, placenta and white adipose tissue.

Cellular localization

Alternative names

NADP-dependent malic enzyme, NADP-ME, Malic enzyme 1, ME1

swissprot:P48163 entrezGene:4199 omim:154250