MEF2B

Function

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.

Sequence Similarities

Belongs to the MEF2 family.

Tissue Specificity

Expressed in skeletal and cardiac muscle and brain.

Cellular localization

• Nucleus

Alternative names

XMEF2, MEF2B, Myocyte-specific enhancer factor 2B, RSRFR2, Serum response factor-like protein 2

Database links

swissprot:Q02080 omim:600661 entrezGene:4207 entrezGene:100271849