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MEIS3

Function

Transcriptional regulator which directly modulates PDPK1 expression, thus promoting survival of pancreatic beta-cells. Also regulates expression of NDFIP1, BNIP3, and CCNG1.

Sequence Similarities

Belongs to the TALE/MEIS homeobox family.

Cellular localization

Alternative names

MRG2, MEIS3, Homeobox protein Meis3, Meis1-related protein 2

swissprot:Q99687 entrezGene:56917