Melatonin receptor type 1A

High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Belongs to the G-protein coupled receptor 1 family.

Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus.

• Cell membrane
• Multi-pass membrane protein

Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A

• entrezGene:4543
• omim:600665
• swissprot:P48039

Proteins

Metabolism

39375Da