MELTF
Function
Involved in iron cellular uptake. Seems to be internalized and then recycled back to the cell membrane. Binds a single atom of iron per subunit. Could also bind zinc.
Sequence Similarities
Belongs to the transferrin family.
Tissue Specificity
Found predominantly in human melanomas and in certain fetal tissues; also found in liver, epithelium, umbilical chord, placenta and sweat gland ducts.
Cellular localization
- Isoform 1
- Cell membrane
- Lipid-anchor
- GPI-anchor
Alternative names
CD228, MAP97, MFI2, MELTF, Melanotransferrin, Melanoma-associated antigen p97