METTL15
Function
N4-methylcytidine (m4C) methyltransferase responsible for the methylation of position C839 in mitochondrial 12S rRNA (PubMed:31665743, PubMed:32371392). Involved in the stabilization of 12S rRNA folding, therefore facilitating the assembly of the mitochondrial small ribosomal subunits (PubMed:31665743, PubMed:32371392).
Sequence Similarities
Belongs to the methyltransferase superfamily. RsmH family.
Cellular localization
- Mitochondrion matrix
Alternative names
METT5D1, METTL15, 12S rRNA N(4)-cytidine methyltransferase METTL15, 12S rRNA m4C methyltransferase, Methyltransferase 5 domain-containing protein 1, Methyltransferase-like protein 15