MIS12
Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270). Essential for proper kinetochore microtubule attachments (PubMed:23891108).
Sequence Similarities
Belongs to the mis12 family.
Cellular localization
- Chromosome
- Centromere
- Kinetochore
- Associated with the kinetochore.
Alternative names
Protein MIS12 homolog, MIS12