Mitochondrial inner membrane protein OXA1L
Function
Mitochondrial membrane insertase that mediates the cotranslational insertion of integral membrane proteins into the mitochondrial inner membrane (PubMed:17936786, PubMed:33602856, PubMed:7991568). Essential for the activity and assembly of cytochrome oxidase (PubMed:17936786, PubMed:7991568). Required for the correct biogenesis of ATP synthase and complex I in mitochondria (PubMed:17936786, PubMed:7991568).
Sequence Similarities
Belongs to the OXA1/ALB3/YidC family.
Cellular localization
- Mitochondrion inner membrane
- Multi-pass membrane protein
Alternative names
Mitochondrial inner membrane protein OXA1L, OXA1Hs, Oxidase assembly 1-like protein, OXA1-like protein, OXA1L