MOB4
Function
Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation.
Post-translational modifications
Phosphorylated on serine residues.
Sequence Similarities
Belongs to the MOB1/phocein family.
Cellular localization
- Cytoplasm
- Perinuclear region
- Membrane
- Peripheral membrane protein
- Golgi apparatus
- Golgi stack membrane
- Peripheral membrane protein
- In a perinuclear punctate pattern. Associated with membranes and the Golgi stacks.
Alternative names
MOB3, MOBKL3, PHOCN, PREI3, CGI-95, MOB4, MOB-like protein phocein, 2C4D, Class II mMOB1, Mob1 homolog 3, Mps one binder kinase activator-like 3, Preimplantation protein 3, Mob3