MOK protein kinase

Able to phosphorylate several exogenous substrates and to undergo autophosphorylation. Negatively regulates cilium length in a cAMP and mTORC1 signaling-dependent manner.

Autophosphorylated.

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Expressed in heart, brain, lung, kidney, and pancreas, and at very low levels in placenta, liver and skeletal muscle. Detected in retina.

• Cytoplasm
• Cell projection
• Cilium
• Nucleus

RAGE, RAGE1, MOK, MAPK/MAK/MRK overlapping kinase, MOK protein kinase, Renal tumor antigen 1, RAGE-1

• entrezGene:5891
• omim:605762
• swissprot:Q9UQ07

Proteins

Oncology

48014Da